Alternative Names:

LMN; ADLD; LMN2; LMNB; Lamin B1;

Purification:

Affinity-chromatography 

Specificity:

Lamin B1 Antibody detects endogenous levels of total Lamin B1 

Immunogen:

A synthesized peptide derived from human Lamin B1 

Description:

The nuclear lamina consists of a twoDimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. 

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.