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DEPC CAS:1609-47-8 Diethyl pyrocarbonate
发布时间:2023-10-17     作者:LYQ   分享到:

DEPC 是一种**的、不可逆的含有组氨酸残基的 RNase 抑制剂。DEPC 可用碳氧基化修饰组氨酸残基从而导致酶失活,可用于防止RNA 酶降解RNA。DEPC 对兔子的中枢化学敏感性具有抑制作用。DEPC 可以修饰 His,Tyr,Ser 和 Thr 残基。

别名 Diethyl pyrocarbonate

分子量 162.14

分子式 C6H10O5

CAS No. 1609-47-8

存储

Powder: -20°C for 3 years | In solvent: -80°C for 2 years

溶解度

DMSO: 90.0 mg/mL (555.1 mM), Need ultrasonic

H2O: 30.0 mg/mL (185.0 mM)

( < 1 mg/mL refers to the product slightly soluble or insoluble )

产品描述 DEPC is a potent and irreversible RNase inhibitor containing histidine residues.DEPC can be used to prevent RNA enzyme degradation by modifying histidine residues with carboxylation resulting in enzyme inactivation. DEPC showed inhibitory effect on the central chemical sensitivity of rabbits. DEPC modified His, Tyr, Ser and Thr residues.

体内活性 Insulin binding to rat liver plasma membranes is inhibited in a time- and dose-dependent fashion by prior treatment of membranes with the histidine-specific reagent diethyl pyrocarbonate.[1]

包装: 瓶装

产地:西安

温馨提示:本品仅适用于科研实验!

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