中文名称:聚乳酸-聚乙二醇-巯基
英文名称:PLA-PEG-SH
纯度:≥95%
分散度:≤1.05
保存:避光除湿,-20°条件下长期保存
巯基可以与谁反应?
巯基(SH)可以与马来酰亚胺发生反应。聚乙二醇增加药物溶解度和稳定性,减少多肽和蛋白质的免疫原性, 抑制带电分子在修饰表面的非特异性结合。可修饰蛋白质、多肽和其它小分子材料。
产品应用:
广泛应用于医药研究、药性缓释、纳米新材料研究、细胞培养。在活性化合物的配体研究,多肽合成载体,高分子接枝化合物,新型材料的聚乙二醇涂层及修饰功能化方面的应用成为研究趋势
PLA-PEG-SH结构式:
Product introduction:
Mercapto group can react with maleimide. Polyethylene glycol can increase the solubility and stability of drugs, reduce the immunogenicity of peptides and proteins, and inhibit the non-specific binding of charged molecules on the modified surface. It can modify proteins, peptides and other small molecular materials. It is widely used in pharmaceutical research, drug sustained release, nano new material research and cell culture. It has become a research trend in the research of ligands of active compounds, peptide synthesis carriers, polymer graft compounds, polyethylene glycol coatings of new materials and the application of modification and functionalization
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