产品名称:
4-amino-1,8-Naphthalimide,1742-95-6,6-amino-1H-benz[de]isoquinoline-1,3(2H)-dione
产地:西安
规格:1mg 5mg 10mg
纯度:99%
用途:仅用于科研
温馨提示:仅用于科研,不能用于人体实验!
The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis, particularly in response to reactive oxygen and nitrogen species.1,2 4-amino-1,8-Naphthalimide (4-ANI) is an inhibitor of PARP (IC50 = 180 nM).3 It blocks radiation-induced PARP in cancer cells, potentiating the cytotoxicity of γ-radiation, although it is not cytotoxic in the absence of radiation.4 4-ANI is used to study the role of PARP activity in various cell systems.
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编辑:XAQYBIO HAO,2023年3月15日。