ME0328,1445251-22-8
发布时间:2023-03-20     作者:hao   分享到:
产品名称:
ME0328,1445251-22-8
产地:西安
规格:1mg 5mg 10mg
纯度:99%
用途:仅用于科研
温馨提示:仅用于科研,不能用于人体实验!
The poly(ADP-ribose) polymerases (PARPs) are enzymes with roles in DNA repair, apoptosis, inflammation, and other cellular events, particularly in response to reactive oxygen and nitrogen species.1,2 ME0328 is an inhibitor of PARP3 (IC50 = 0.89 µM), which is a regulator of DNA repair and mitotic progression.3 It displays selectivity for PARP3 over 12 other PARP family members. ME0328 is cell permeable and elicits PARP3-specific effects at submicromolar concentrations.
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编辑:XAQYBIO HAO,2023年3月15日。