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CAS:77337-73-6 Acamprosate (calcium) 阿坎酸钙 路线研究
发布时间:2024-04-07     作者:kx   分享到:

中文名 阿坎酸钙

英文名 acamprosate calcium

中文别名 3-(乙酰氨基)丙烷磺酸钙 | 乙酰高牛磺酸钙

熔点 >300ºC

分子式 C5H10NO4S.1/2Ca

分子量 200.24

PSA 189.36000

LogP 1.05900

外观性状 白色,无气味的或几乎无气味的粉末

储存条件 Room temp

水溶解性 水溶性:完全溶解

"Acamprosate calcium(Campral EC) is a GABA receptor agonist and modulator of glutamatergic systems; reduces alcohol consumption in animal models of alcohol addiction.

IC50 value:

Target: GABA receptor

Acamprosate, or N-acetyl homotaurine, is an N-methyl-D-aspartate receptor modulator approved by the Food and Drug Administration (FDA) as a pharmacological treatment for alcohol dependence.Acamprosate has low bioavailability, but also has an excellent tolerability and safety profile. In comparison with naltrexone and disulfiram, which are the other FDA-approved treatments for alcohol dependence, acamprosate is unique in that it is not metabolized by the liver and is also not impacted by alcohol use, so can be administered to patients with hepatitis or liver disease (a common comorbid condition among individuals with alcohol dependence) and to patients who continue drinking alcohol."

CAS:77337-73-6	Acamprosate (calcium)	阿坎酸钙     路线研究

包装:100mg,500mg,1g,10g,100g以及kg级别等公斤级大包装

纯度:99%

配送:惯例下常温**

包装:袋装

厂家:西安齐岳生物科技有限公司

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