TPE-Ph-In
TPE-Ph-In was thus chosen for cell staining test. Pre-experiment showed that this dye is cell permeable and stain mitochondria specifically. Compared with TPE-TPP, the UV-excited AIE mitochondrial probe with blue-emission previously developed in our group, TPE-Ph-In can be well excited with a 488 nm laser and therefore more compatible with confocal microscope and manifest higher signal-to-noise ratio (Fig. S11). To test the mitochondrial selectivity of TPE-Ph-In, a co-localization experiment was performed with commercial CellLight® Mitochondria-GFP (Mito-GFP), a green fluorescent protein targeted to mitochondria. The stained cells give out red fluorescence from TPE-Ph-In and green fluorescence from Mito-GFP (Fig. 2A and 2B), respectively. Merged image shows that the distribution of TPE-Ph-In in cells is totally consistent with that of Mito-GFP, indicating the high selectivity of TPE-Ph-In towards mitochondria.
四苯基乙烯(TPE)及其衍生物具有聚集诱导发光特性,在光电材料等领域应用前景广。齐岳生物提供功能化的四苯乙烯(TPE)及其衍生物。
AIE材料的构筑离不开其核心AIE基元,例如:三苯胺TPA、四苯基乙烯、苯基取代噻咯、苯基乙烯蒽和苯基取代吡咯等。
定制产品:
BITB的AIEgens
BITB、BITT、ITT、ITB
TPBi、TCTA、TAPC、HATCN
TPE-PTB(AIE)
TPE-PTB纳米粒子(AIE NPs)
PTB-TFB
TAE小分子、含TAE结构单元的聚合物
4TPA-BQ
四硝基-四苯基乙烯(TPE-4N)
AIE化合物TVP-S
TVP-PAP探针
具有AIE活性的苯并噻二唑和四苯基乙烯(TPE)的共轭聚合物(PTB-APFB)
TPE-(Im)- 2
TPE-Im
TPE-(Im)2
SeSe-(P5)-2
TBP-1、TBP-2
具有AIE活性的TBP分子
TBP-e-TPA分子
TBP-b-TPA 纳米粒子
以上资料来自西安齐岳生物小编zhn2021.08.02
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